Aniracetam

Glossary / Nootropics / Aniracetam
NOOTROPICS · GLOSSARY ENTRY

Aniracetam

A fat-soluble racetam — generally characterised as anxiolytic and mood-elevating in addition to the cognitive effects of piracetam.

Why it matters

Aniracetam is lipid-soluble (unlike water-soluble piracetam), which speeds crossing of the blood-brain barrier. It acts as a positive allosteric modulator at AMPA receptors and has effects on the cholinergic, serotonergic, and dopaminergic systems. The serotonergic activity is the proposed mechanism for the reported anxiolytic effect.

In practice

Typical doses are 750mg–1.5g daily, taken with food due to fat solubility. Effects are reported faster than piracetam (within hours) and qualitatively warmer.

Common confusion

Aniracetam is sometimes claimed to “directly cure anxiety.” The effect is closer to a modest, situational anxiolytic.

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